The manufacturer does recommend that Toprol XL (Metoprolol Succinate) be taken with or immediately following a meal. In conclusion, there is no specific time recommended that Toprol XL (Metoprolol Succinate) should be taken. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. Some other common side effects reported in patients on Toprol XL (Metoprolol Succinate) include: It is possible that your sleepiness in the afternoon can be from this medication. One of the commons side effects of Toprol XL (Metoprolol Succinate) can be fatigue, which can occur in 1% to 10% of patients that take this drug. It is a fairly common recommendation to take blood pressure medication in the evening as this can help reduce dizziness or fatigue in some individuals. Doing this once to change your dosing schedule should not cause any problems. This means that there will still be some drug left in your body even if you push your next dose off by a couple hours. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. The half-life of a drug is the time it take for the amount of drug in the body to be reduced by one-half. This medication is a beta-blocker used to treat chest pain (angina), heart failure, and high blood pressure. The half-life of Toprol XL (Metoprolol Succinate) is 24 hours. With or after your evening meal would be fine to take Toprol XL (Metoprolol Succinate). Besides this, there is no specific recommended time to take this drug. It is recommended by the drug manufacturer that Toprol XL (Metoprolol Succinate) be preferably taken with or immediately following a meal for best absorption. It is indicated to be used in the following conditions: Toprol XL (Metoprolol Succinate) is a selective beta-blocker. But maybe it's just whatever I had for lunch. Because it's extended release, does it make a difference when I take it? Will it also help me by being sleepier in the evening, then during the work day? Sometimes it seems like I'm sleepy after taking it. So that when school starts back I won't need to take it there. I'm thinking about gradually taking it a little later in the day. Salicylates may reduce the antihypertensive effects of beta-blockers. The tartrate is an immediate-release formulation and the succinate is an extended-release formulation. Oral contraceptives may increase the AUC and Cmax of Metoprolol 25 MG Tablet. The active substance metoprolol is employed either as metoprolol succinate or as metoprolol tartrate (where 100 mg metoprolol tartrate corresponds to 95 mg metoprolol succinate). The tablets contain 23.75, 47.5, 95 and 190 mg of metoprolol succinate equivalent to 25, 50, 100 and 200 mg of metoprolol tartrate, USP, respectively. Each pellet acts as a separate drug delivery unit and is designed to deliver metoprolol continuously over the dosage interval.
NSAIDs (ibuprofen, indomethacin, naproxen, piroxicam) may reduce the antihypertensive effects of beta-blockers. metoprolol succinate in a multitude of controlled release pellets. My doctor said to just take it once a day at the same time. Metoprolol 25 MG Tablet reduces antipyrine's clearance by 18.